(1) If the Karakas (significators) of the Bhavas are inimical to those Bhavas (houses), and if the owners of the Rasi and Navamsa having the lord of the bhava are hostile to the Bhava and its significator, the effects of the concerned Bhava are ruined. (2) If a malefic is posited in a sign owned by a Karaka (significator), it destroys the effect to be given by the significator. (3) A malefic occupying a sign owned by a significator will lessen the effects of that Bhava.